Drug Development: It aids in understanding the interaction between drugs and
biomolecular targets, leading to the discovery and optimization of therapeutic agents.
Diagnostics: Biomolecular analysis helps in the detection of
biomarkers for various diseases, enabling early diagnosis and monitoring of disease progression.
Basic Research: It provides insights into the fundamental processes of life, including gene expression, protein function, and cellular signaling.
Mass Spectrometry (MS): Used for identifying and quantifying biomolecules by measuring their mass-to-charge ratio.
Chromatography: Techniques like HPLC and GC are used to separate and analyze biomolecules based on their physical and chemical properties.
Nuclear Magnetic Resonance (NMR) Spectroscopy: Provides detailed information about the structure and dynamics of biomolecules.
X-ray Crystallography: Used to determine the atomic structure of crystallized biomolecules.
ELISA (Enzyme-Linked Immunosorbent Assay): A widely used technique for detecting and quantifying proteins and other antigens.
PCR (Polymerase Chain Reaction): Amplifies small amounts of DNA for various applications, including genetic analysis and cloning.
Complexity: Biological samples often contain complex mixtures of biomolecules, making their analysis challenging.
Sensitivity: Detecting low-abundance biomolecules requires highly sensitive analytical techniques.
Specificity: Differentiating between similar biomolecules demands highly specific methods.
Sample Preparation: Proper preparation and handling of samples are critical to avoid degradation and contamination.
Miniaturization: Developing
microfluidic devices for high-throughput and cost-effective biomolecular analysis.
Automation: Integrating automated systems to enhance reproducibility and efficiency.
Multi-omics: Combining genomics, proteomics, metabolomics, and other -omics technologies for comprehensive biological insights.
Single-molecule Analysis: Advancing techniques to analyze individual molecules for detailed understanding of molecular mechanisms.
