Physiologically Based Pharmacokinetic (pbpk) Models - Bioanalytical Research

Relevant Publications

Novel Omeprazole Delayed Release Orally Disintegrating Tablets for Enhanced Patient Compliance: A Case of Model Informed Formulation Development.

Issue Release: 2024

Investigating pharmacokinetic profiles of using machine learning and PBPK modelling.

Issue Release: 2024

Evaluation of Various Approaches to Estimate Transplacental Clearance of Vancomycin for Predicting Fetal Concentrations using a Maternal-Fetal Physiologically Based Pharmacokinetic Model.

Issue Release: 2024

Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population.

Issue Release: 2024

Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.

Issue Release: 2024

Beyond the basics: A deep dive into parameter estimation for advanced PBPK and QSP models.

Issue Release: 2024

Dose Optimization Informed by PBPK Modeling: State-of-the Art and Future.

Issue Release: 2024

Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models.

Issue Release: 2024

Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies.

Issue Release: 2024

Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding.

Issue Release: 2024

Development of a physiologically based pharmacokinetic model for levetiracetam in patients with renal impairment to guide dose adjustment based on steady-state peak/trough concentrations.

Issue Release: 2024

Docetaxel, cyclophosphamide, and epirubicin: application of PBPK modeling to gain new insights for drug-drug interactions.

Issue Release: 2024

Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins.

Issue Release: 2024

Pharmacokinetic Modeling of Bepotastine for Determination of Optimal Dosage Regimen in Pediatric Patients with Allergic Rhinitis or Urticaria.

Issue Release: 2024

Sex, Age, and Species Differences of Perfluorooctanoic Acid Modeled by Flow- versus Permeability-limited Physiologically-Based Pharmacokinetic Models.

Issue Release: 2024

Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model.

Issue Release: 2024

Human Pharmacokinetic and CYP3A Drug-Drug Interaction Prediction of GDC-2394 Using Physiologically Based Pharmacokinetic Modeling and Biomarker Assessment.

Issue Release: 2024

A literature review of drug transport mechanisms during lactation.

Issue Release: 2024

Physiologically based pharmacokinetic modeling in obesity: applications and challenges.

Issue Release: 2024

A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans.

Issue Release: 2024

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Physiologically Based Pharmacokinetic (pbpk) Models - Bioanalytical Research

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