While it is challenging to completely eliminate false negatives, several measures can be taken to minimize their occurrence. These include optimizing assay sensitivity, ensuring proper quality control measures, and using multiple confirmatory tests to validate results. Regular calibration and maintenance of analytical instruments, along with rigorous training of personnel, can also help reduce the likelihood of false negatives. Additionally, improving sample handling and storage protocols can mitigate the risk of sample degradation, which might otherwise contribute to false-negative results.
