Mass spectrometry continues to evolve with advancements in technology and methodology. Innovations include:
Improved Ionization Techniques: New ionization methods, such as Desorption Electrospray Ionization (DESI), allow for the analysis of samples with minimal preparation. Higher Resolution and Sensitivity: Advances in mass analyzer technology, such as the development of high-resolution orbitrap and triple quadrupole instruments, enhance the sensitivity and specificity of MS analyses. Integration with Other Techniques: Combining MS with chromatographic techniques (e.g., LC-MS and GC-MS) and imaging techniques (e.g., MS imaging) provides complementary information and expands the scope of applications. Automation and Miniaturization: Developing automated sample preparation and miniaturized MS instruments enhances throughput and accessibility.
