The discovery of predictive biomarkers involves several steps, including:
Biomarker Identification: Utilizing techniques such as genomics, proteomics, and metabolomics to identify potential biomarkers. Validation: Confirming the clinical relevance of the identified biomarkers through rigorous testing and validation. Analytical Methods: Developing and optimizing bioanalytical methods to accurately measure the biomarkers in biological samples. Clinical Trials: Conducting clinical trials to establish the predictive value of the biomarkers in different patient populations.