How Do Surface Properties Influence Biomolecule Interactions?
Surface properties, such as hydrophobicity, charge, and topography, can dictate how biomolecules interact with surfaces. For example, a hydrophobic surface may promote the adsorption of proteins, but it can also lead to denaturation and loss of function. Conversely, a hydrophilic surface may facilitate better orientation and activity of biomolecules. Surface charge can influence electrostatic interactions, affecting the binding affinity and kinetics of biomolecular interactions.
