Despite its potential, biomarker discovery faces several challenges. These include:
Complexity of biological systems: The human body is highly complex, and identifying a single biomarker that can reliably indicate a disease state is challenging. Variability: Biological variability between individuals and populations can make it difficult to identify universal biomarkers. Validation: Once potential biomarkers are identified, they need to be rigorously validated in large and diverse populations. Ethical concerns: The use of biological samples for research must adhere to ethical standards and obtain necessary consents.
