Several challenges must be addressed to improve drug delivery systems:
- Solubility: Many drugs have poor water solubility, making it difficult for them to be absorbed into the bloodstream. - Stability: Drugs must remain stable during storage and after administration. - Bioavailability: The proportion of the drug that reaches systemic circulation and can have an active effect. - Targeting: Ensuring the drug reaches the intended site of action without affecting other parts of the body.