Recent advances in HPLC technology have further enhanced its capabilities:
UHPLC: Ultra-High-Performance Liquid Chromatography (UHPLC) allows for faster and more efficient separations compared to traditional HPLC. Multidimensional HPLC: Combines two or more columns with different separation mechanisms to achieve higher resolution. Online HPLC-MS: Coupling HPLC with mass spectrometry provides detailed structural information about the analytes.