Various techniques can be employed to enhance detection sensitivity in bioanalytical methods:
Mass spectrometry (MS): Highly sensitive technique for detecting and quantifying small molecules. Liquid chromatography (LC): Often coupled with MS for better separation and detection of analytes. Fluorescence detection: Used in conjunction with techniques like HPLC for detecting fluorescently labeled compounds. Enzyme-linked immunosorbent assay (ELISA): Sensitive method for detecting proteins and antibodies.