CEC operates by using an electric field to drive the mobile phase through a capillary column packed with a stationary phase. The electric field induces electroosmotic flow (EOF), which propels the mobile phase and analytes through the column. This results in high-resolution separations due to the narrow band dispersion typically associated with EOF. The separation mechanism in CEC is influenced by both electrophoretic mobility and chromatographic interactions with the stationary phase.
