1. Sample Collection: Biological samples are collected from the crime scene, suspects, or victims. 2. Extraction: DNA is extracted from the cells in the sample. 3. Amplification: Polymerase Chain Reaction (PCR) is used to amplify specific regions of the DNA. 4. Separation and Analysis: Gel electrophoresis or capillary electrophoresis separates the amplified DNA fragments based on size. 5. Comparison: The resulting DNA profile is compared to profiles in a database or other samples to find matches.