What are the Challenges in Analyzing Complex Biological Matrices?
Analyzing complex biological matrices presents several challenges:
1. Matrix Effects: The presence of multiple interfering substances can affect the accuracy and precision of analytical measurements. 2. Sample Preparation: Efficiently extracting and isolating the target analyte without losing its integrity or altering its concentration is difficult. 3. Sensitivity and Specificity: The need for highly sensitive and specific analytical methods to detect low-abundance analytes amidst a plethora of other components. 4. Quantification: Establishing reliable quantification methods that can account for the variability in biological samples.
