Blank QC Samples: Contain no added analyte and are used to monitor any background noise or contamination. Low QC Samples: Contain a low concentration of the analyte and are used to assess the method's sensitivity and lower limit of quantification. Medium QC Samples: Contain a mid-range concentration of the analyte and are used to evaluate the method's accuracy and precision within the linear range. High QC Samples: Contain a high concentration of the analyte and are used to ensure that the method can accurately quantify high analyte levels.